Insoluble Glucan Synthesis by Mutansucrase as a Determinant of the Cariogenicity of Streptococcus mutans
نویسندگان
چکیده
منابع مشابه
Cariogenicity of Streptococcus mutans Glucan-Binding Protein Deletion Mutants
Streptococcus mutans is a principal etiologic agent in the development of dental caries due to its exceptional aciduric and acidogenic properties, and its ability to adhere and accumulate in large numbers on tooth surfaces in the presence of sucrose. Sucrose-dependent adherence is mediated by glucans, polymers of glucose synthesized from sucrose by glucosyltransferase (Gtf) enzymes. S. mutans m...
متن کاملCharacterization of an anti-glucosyltransferase serum specific for insoluble glucan synthesis by Streptococcus mutans.
An anti-glucosyltransferase serum, which synthesized 96% insoluble glucans, was prepared against a purified enzyme preparation from Streptococcus mutans strain HS6 (serotype a). This serum was examined for its effects on glucan synthesis by crude enzyme preparations from eight strains (four serotypes) of S. mutans and for the ability of these preparations to promote adherence of S. mutans to a ...
متن کاملCloning of a Streptococcus mutans glucosyltransferase gene coding for insoluble glucan synthesis.
The gtfB gene coding for a glucosyltransferase (GTF) activity of Streptococcus mutans GS-5 was isolated on a 15.4-kilobase DNA fragment by using a lambda L47.1 gene library. The activity was catalyzed by gene products of 150 and 145 kilodaltons which reacted with antibodies directed against both soluble and insoluble glucan-synthesizing GTFs. The enzyme present in crude Escherichia coli extract...
متن کاملIndependence of water-insoluble glucan synthesis and adherence of Streptococcus mutans to smooth surfaces.
Water-insoluble glucans (WIG) produced from sucrose by Streptococcus mutans glucosyltransferases (GTases) are of major importance in the adherence and colonization of the organisms on tooth surfaces and the subsequent development of dental caries [ 1,2]. In fact, mutants of S. mutans which lack the ability to synthesize WIG do not stick to glass surfaces and do not induce smoothsurface-caries f...
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تلمیح یکی از عناصری است که تقریباً در همه ی متون ادبی یافت و باعث ایجاد شکاف های فرهنگی می شود. در این تحقیق به عنوان شکلی از بینامتنیت در ترجمه مورد توجه قرار می گیرد. تلاش شده است تا راهکارهای مترجمان برای ترجمه چهار نوع اسامی خاص و عبارات کلیدی تلمیحی (مذهبی، سیاسی، تاریخی و اسطوره ای) موجود در رمانِ چهره مرد هنرمند در جوانی به فارسی بررسی شود. این تحقیق مقایسه ای بر اساس راهکارهای ترجمه تلمیح...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1981
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-127-2-407